BDBM50153593 CHEMBL3775351::US10053456, 123::US10414761, Example 123::US10968213, Example 123::US9487511, 123::US9718814, 123::US9920047, 123

SMILES Cc1sc(cc1[C@@H]1C[C@H]1NC1CCC1)C(=O)Nc1cnn(C)c1

InChI Key InChIKey=FNFVTNNWNCYKMO-LSDHHAIUSA-N

Data  43 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153593   

TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153593(CHEMBL3775351 | US10053456, 123 | US10414761, Exam...)
Affinity DataIC50: <100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153593(CHEMBL3775351 | US10053456, 123 | US10414761, Exam...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent